Detailed Agenda - 11th International Symposium on Neurovirology

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Wednesday, 30 May

7:00 am - 8:00 am

Continental Breakfast


8:00 am - 8:30 am

Welcoming Remarks


8:30 am - 9:45 am

Session I

Brain as a reservoir for HIV

    Session Chairs: David Volsky and Bruce Brew
8:30 am

Christopher Power (Plenary)
University of Alberta, Edmonton, Alberta, Canada

Brain lentivirus burden and neurovirulence-strategies for establishing a fine balance
9:00 am

Wenxue Li
National Institute of Neurological Diseases and Stroke, National Institutes of Health, Bethesda, MD, USA

Activation of HERV-K expression by HIV-1 infection
9:15 am

David Alvarez-Carbonell
Case Western Reserve University, Cleveland, OH, USA

The Nurr1/CoREST transrepression pathway impairs HIV reactivation in latently infected microglial cells
9:30 am
Andrew MacLean
Tulane University, New Orleans, LA, USA
Priming the pump: Tat primes astrocytes for subsequent cytokine secretion, quantitative morphological changes and BBB disruption through TLR2

9:45 am - 10:05 am

Coffee Break


10:05 am - 10:35 am

Special Lecture

2012 Neurological Infections Lectureship

    Introduction by Lynn Pulliam
  Carol Glaser
California Department of Public Health, Richmond, CA, USA
Overview of infectious encephalitis – Lessons learned from the California Encephalitis Project

10:35 am - 11:50 am

Session II

Neuroimaging and surrogate markers in HAND

    Session Chairs: Kelly Jordan-Sciutto and Ron Ellis
10:35 am
Ramon Gilberto Gonzalez (Plenary)
Massachusetts General Hospital, Boston, MA, USA
Neuroimaging of brain viral dynamics and neuronal injury in HAND
11:05 am
Vanessa Pirrone
Drexel University College of Medicine, Philadelphia, PA, USA
Impact of age on markers of HIV-1 disease
11:20 am
James T. Becker
University of Pittsburgh, Pittsburgh, PA, USA
MEG-identified recovery of CNS functional connectivity in HIV disease after HAART
11:35 am
Carlos Barrero
Temple University School of Medicine, Philadelphia, PA, USA
SILAC-based quantitative proteomic approach to identify HIV-1 Vpr mediated changes in macrophage metabolic pathways

11:50 am - 1:20 pm

Lunch Break / Networking


1:20 pm - 2:35 pm

Session III

Neurobehavioral challenges and therapeutic advances

    Session Chairs: Victor Valcour, Olimpia Meucci
1:20 pm
Fatah Kashanchi (Plenary)
George Mason University, Manassas, VA, USA
Viral miRNA and exosomes: Possible control of cellular signaling pathways in uninfected cells
1:50 pm
José A. Muñoz-Moreno
Germans Trias i Pujol University Hospital, Barcelona, Spain
Differences in North American and West European study populations when detecting neurocognitive impairment in HIV infection: A comparison of three screening methods
2:05 pm
Walter Royal, III
University of Maryland School of Medicine, Baltimore, MD, USA
Neurocognitive impairment among treatment-naïve, HIV-infected individuals in Nigeria
2:20 pm
JoEllyn McMillan
University of Nebraska Medical Center, Omaha, NE, USA
Cell-targeted long-acting nanoformulated antiretroviral therapy

2:35 pm - 3:05 pm

Special Lecture

2012 Women in Neuroscience Lectureship

    Introduction by Eugene O. Major
  Joan W. Berman
Albert Einstein College of Medicine, Bronx, NY, USA
Mechanisms of neuroinflammation and toxicity: Critical roles in NeuroAIDS

3:05 pm - 3:25 pm

Coffee Break


3:25 pm - 4:40 pm

Session IV

Viral latency, molecular pathogenesis, and malignancy

    Session Chairs: Giulio Tarro and Igor Koralnik
3:25 pm
Charles S. Cobbs (Plenary)
California Pacific Medical Center, San Francisco, CA, USA
Emerging role of cytomegalovirus in malignant glioma
3:55 pm
Xin Dang
Beth Israel Deaconess Medical Center, Boston, MA, USA
JC virus encephalopathy is associated with a novel Agnoprotein-deletion JCV variant
4:10 pm
Te Du
University of Chicago, Chicago, IL, USA
The activation of latent herpes simplex virus and suppression of LAT and mi-RNAs in trigeminal ganglia within the time-frame of a single cycle of viral replication
4:25 pm
Benjamin Gelman
University of Texas Medical Branch, Galveston, TX, USA
HIV latency and viral DNA caches in the human brain: Post-integration DNA is highest in specimens obtained prior to HAART and is enriched in white matter

7:00 pm - 9:30 pm

Special Activity

Women in NeuroVirology Reception

Regency Room

  Panel Discussion

Moderator: Joan Berman

    Panelists: Shilpa Buch, Jennifer Gordon, Diane Lawrence, Aimee Luers, and Susan Morgello

Shading indicates presentations associated specifically with the 2012 Conference on HIV in the Nervous System

Wednesday, 30 May